Found 14 matching trials
Shortening Treatment by Advancing Novel Drugs PHASE3 The purpose of this study is to assess the efficacy, safety and tolerabilit...
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National Center for Tuberculosis and Lung Diseases
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Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z) PHASE2 The trial will evaluate the extended bactericidal activity of 14 consecutiv...
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Centre for Tuberculosis Research Innovation, UCT Lung Institute
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Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis PHASE3 To evaluate the efficacy, safety and tolerability of various doses and dura...
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National Center for Tuberculosis and Lung Diseases
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A Phase 2 to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide in Adult Subjects With Drug-Sensitive or Multi Drug-Resistant Pulmonary Tuberculosis. PHASE2 The purpose of this study is to determine the mycobactericidal activity of ...
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The Aurum Institute: Tembisa Hospital
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Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects PHASE1 This is a Phase 1, single-center, randomized, balanced, single-dose, two-tr...
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MDS Pharma Services
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Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-009) PHASE1 This will be a Phase 1, single-center, randomized, balanced, single-dose, t...
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MDS Pharma Services (Celerion)
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Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001) PHASE2 The trial will evaluate the extended bactericidal activity of 14 consecutiv...
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Centre for Tuberculosis Research Innovation, UCT Lung Institute
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A Phase 3 Trial Assessing Safety and Efficacy of B-Pa-L in Participants With DR-TB PHASE3 The purpose of this study is to evaluate the efficacy, safety, tolerability...
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Task Applied Science - Brooklyn Chest Hospital
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Economic Evaluation of New MDR TB Regimens PHASE2 The current treatment regimen for MDR-TB has poor outcomes and costs of tre...
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Republican Scientific and Practical Centre for Pulmonology and Tuberculosis hospital
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Pretomanid in Adults With Hepatic Impairment PHASE1 This is a Phase 1, single dose (200 mg), open-label study comparing the pha...
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Saint Louis University Center for Vaccine Development
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